Sotret 30 Mg Capsule

Sotret 30 mg capsule is an isotretinoin formulation that may helps in treating severe acne condition caused by C. acnes bacteria. Isotretinoin may work by reducing sebum production by 80-90% this leads to reduce oil and creates starving condition for bacteria, this may also lower the inflammation and reduces acne and redness.

Key Features

How does Sotret 30 mg Capsule work?

• Sotret 30 mg capsule may shrink your oil glands, may reduce sebum production by 80-90%.
• This may prevent dead sin cells from clogging pores and also reducing comedones.
• This may lower inflammatory cytokines in skin lesions.
• As sebum gets reduces, bacteria get starved to death.

Usage

• It can be used in treating severe recalcitrant nodular acne.
• Acne with scarring or significant psychosocial distress.

Dosage

• It can be taken 1-2 tablets a day, with food.
• Dosage can be adjusted according to individual requirement.

Side effects

• Dry lips
• Dry skin
• Cheilitis
• Dry nasal mucosa
• Back pain
• Arthralgia
• Muscle aches
• Headache

Interactions

• Avoid taking vitamin A supplement with Sotret 30 mg as it may leads to hypervitaminosis.
• If Sotret 30 mg contacts with Tetracyclines the it may lead to raise intracranial pressure.
• The combination of Sotret with alcohol can lead to increase in triglycerides and liver strains.
• Avoid the contact with methotrexate, phenytoin that may increase the hepatotoxicity risk.
• It may lead to severe skin reactions.
• It may can cause psychiatric issues like depression, mood swings, suicidal ideation.

Pharmacokinetics

• The absorption may vary, approx. 25% and approx. 40% without and with food absorption respectively.
• It reaches peak plasma in just 3-5 hours.
• Half-life is about of parent drug is approx. 21 hours, and the main metabolite 4-oxo-isotretinoin is approx. 17-50 hours.
• Metabolism is followed by hepatic metabolism via CYP2C8, CYP2C9, and CYP3A4.
• It can be excreted through urine.

Precautions

• It may lead to severe birth defects.
• Need to monitor for depression and suicidal thoughts and aggression, should avoid if mood changes.
• Avoid waxing, dermabrasion and laser for 6 months after due to scarring risk.
• May leads to dry eyes, need to use lubricating drops.
• Do not donate the blood during treatment to avoid unwanted interactions.
• Prior taking any such medications just go through Dermat advise.

Conclusion

Sotret 30 mg capsule is best and effective isotretinoin formulation that may help in treating severe acne condition caused by C. acnes bacteria. Isotretinoin may work by reducing sebum production by 80-90% this leads to reduce oil and creates starving condition for bacteria, this may also lower the inflammation and reduces acne and redness. It may show some side effects and interactions that may vary from person to person.

FAQs