Accufine 30 mg capsule containing Isotretinoin is a lipophilic drug, that is being used in treating severe nodular acne caused by clogged pores, excessive sebum and also due to Cutibacterium acne bacteria. Accufine 30 mg may work by shrinking sebaceous gland and also by decreasing the sebum production by 90%, and the anti-inflammatory action reduce redness, also may suppresses neutrophil migration. This helps in curing acne prone skin condition.
Key Features
| About Accufine 30 mg Capsule |
|---|
| Drug Class: Dermatological agent |
| Subclass: Retinoid |
| Active Ingredient: Isotretinoin |
| Product Details | |
|---|---|
| Composition | Active Ingredient: Isotretinoin
Inactive Ingredients: |
| Packaging Type | Blister |
| Pack Size | 10*3 |
| Dosage | 30 mg |
| Active Ingredient | Isotretinoin |
| Manufacturer | Healing Pharma |
| Shelf Life | 2–3 years from the date of manufacturing |
| Usages | Used in treating severe nodular acne |
| Country of Origin | India |
How does Accufine 30 mg capsule work?
Accufine 30 mg may contains isotretinoin, it is a vitamin A derivative. It may act by targeting all crucial root cause of acne as
- Accufine 30 mg leads to shrink sebaceous gland and cut the sebum production by 90%.
- It acts as anti-comedogenic and prevents pores from clogging.
- Eventually the painful cyst may get reduced and also may suppresses neutrophil migration.
- It indirectly lowers acne and clears the skin within 15-20 weeks. It may vary from individual conditions.
Usage
- It can be used in treatment of Acne.
- In treating Acne conglobate, acne fulminans can also be used.
Dosage
- It can be taken twice a day or dosage can be adjusted according to need.
- It can be taken with food for better results.
Strength of Medication
Side Effects
- Cheilitis
- Muscle Pain
- Mood swings
- Headache
- Fatigue
- Rash
- Itching
- Increased Triglycerides
- Depression
Interaction
- The interaction of Accufine 30 mg with Vitamin A supplements and retinoids can be avoided.
- Tetracyclines may leads to hypertension.
- Alcohol consumption may increase triglyceride and it leads to hepatic toxicity.
- If allergic to isotretinoin then should avoid taking such medications.
- It can also increase the risk of osteoporosis.
Pharmacokinetics
- The absorption, approx. 25% without food and 40% with food. It may reach at the peak plasma Tmax = 2-4 hours.
- It is 99.9% bound to plasma proteins, i.e., mainly albumin.
- It may follow hepatic metabolism.
- Due to enterohepatic cycling, the half-life is longer.
- It can be excreted through urine and feces.
Precaution
- Taking Accufine 30 mg can be during pregnancy is very risk so it should be avoided during pregnancy, breast feeding and also while planning pregnancy it may can cause severe birth defects.
- Contact lenses may become intolerable due to dry eyes.
- Avoid taking Vitamin A supplement with isotretinoin tablets like Accufine 30 mg.
- If you notice symptoms like mood changes, depression or sleep issues then need to avoid such medications.
- Lips, eye, skin will get dry due to shrinkage in sebaceous gland then start applying lip balm, moisturizer and eye drop to get over dryness.
- Do not donate your blood during treatment and also skip the next month.
Conclusion
Accufine 30 mg is a best and effective medication in treating severe, scarring, nodular acne caused by clogged pores, excessive sebum and also due to Cutibacterium acne bacteria. Accufine 30 mg may work by shrinking sebaceous gland and also by decreasing the sebum production by 90%, and the anti-inflammatory action reduce redness, also may suppresses neutrophil migration. This helps in curing acne prone skin condition. This may have some interactions and may lead to side effects to avoid then just follow the instructions of your Dermat for better results.
Fernandez –
Worked really well. My skin did dry out because of it but I just used some moisturizer