Anti Worms

An antiworm drug is also known to be as anthelmintic is a medication specifically formulated to killer expel parasitic worms i.e., helminth from the body. Helminths are multicellular parasites i.e., nematodes, cestodes, trematodes. Antiworm drugs do not work on protozoa like Giardia, bacteria, viruses or fungi. This antiworm drugs do not work on protozoa like Giardia, bacteria, viruses or fungi. Those need different parasitic or antimicrobial drugs. Read More

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Helminths or worms may include:

  • Nematodes: This may include roundworms like Ascaris, hookworm, pinworm, whipworm, strongyloidiasis, filarial worms.
  • Cestodes: This may include tapeworms like Taenia solium pork, Taenia saginata beef, and fish tapeworm.
  • Trematodes: This may include flukes like Schistosoma, blood flukes, liver flukes and lung flukes.
Benzimidazole, is a synthetic drug that may kill parasitic helminths i.e., worms by binding to worm β tubulin, disrupting microtubule formation, and also by blocking glucose uptake. This may starve and paralyzes the worm.
Infection Medications Onset of action
Roundworms, Hookworms, whipworms, Giardia in dogs, Tapeworm Taenia Fenbendazole 2-6 hours
Pinworm Enterobius, Roundworm Ascaris, Hookworm, Neurocysticercosis, Hydatid disease Albendazole 2-5 hours
Pinworm Enterobius, Roundworm Ascaris, Hookworm Ancylostoma, Whipworm Trichuris Mebendazole 2-4 hours

Benzimidazole medications deals with worm infection

  • Fenbendazole, it is a benzimidazole antiworm drugs used in treating hookworm, roundworm, and whipworm, Giardia.

Medications: Fensafe 222 mg, Wormentel 150 mg, Wormisect 444 mg, Fenbendazole 150 mg,

  • Albendazole, it is an Anthelmintics drug formulated to treat intestinal worms as well as tissue worm infection like Ascaris, Neurocysticercosis, hydatid disease, roundworm, hookworm and tapeworm etc.

Medications: Albendazole 400 mg, Aldol 400 mg, ZBD 400 mg.

  • Mebendazole, it is an Antiworm medications that deals with intestinal worm like pinworm, roundworm, hookworm, whipworm etc.

Medications: Mebex 100 mg.

How Benzimidazole may work?

  • It binds to parasite β tubulin by blocking microtubule formation in worm cells.
  • It may stop glucose uptake, as worms can’t uptake sugar and this may deplete stored energy.
  • This may paralyze and kills worm just by immobilizing adult worms and larval stages, then they’re expelled.
  • This drug is selective toxic, as human tubulin binds these drugs 250-400 times less strongly than worm tubulin and is considered to be safe at normal dosage.

Safety & Efficacy

  • According to safety concern, it may show some side effects like dizziness, mild nausea, abdominal pain, headache, rash, transient hair loss, this may vary from person to person need to consult healthcare provider prior using any such medications.
  • In the condition of pinworm, roundworm infection there’s 95% cure, in the condition of hookworm there can be 72-95% of cure, in the case of whipworm 50-80% cure and in the case of strongyloidiasis there can be 65-85% cure.
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