Tretiheal Cream 0.05% 20 gm Powerful Retinoid contains Tretinoin. It is a form of vitamin A. This cream is mainly used to treat acne, which appears on your chest, face, and back as pimples or spots. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin.
Key Features
| About | |
|---|---|
| Drug Class | Retinoid |
| Sub class | Topical Retinoid / Keratolytic Agent |
| Active ingredient | Tretinoin (0.05% w/w) |
| Tretiheal Cream 0.05% 20 gm – Powerful Retinoid | |
|---|---|
| Composition |
Active ingredients: Tretinoin (0.05% w/w)
Inactive ingredients:
|
| Packaging Type | Tube |
| Pack Size | 20 gm |
| Dosage | A pea-sized of amount, once daily |
| Active ingredients | Tretinoin (0.05% w/w) |
| Shelf Life | 36 months |
| Usages | To fade hyperpigmentation, to treat acne vulgaris, and to reduce fine surface wrinkles |
How does Tretiheal Cream 0.05% 20 gm Powerful Retinoid work?
Retinoic acid receptors (RARs) are activated by active tretinoin in the skin cells. This helps to alter gene expression to improve skin health. Tretinoin speeds up the loss of outer epidermis layers. Tretiheal Cream 0.05% 20 gm Powerful Retinoid removes dead cells and excessive oils from your skin. As a result, microcomedones, acne vulgaris, and wrinkles start to fade. Along with that, your skin becomes elastic through deep dermal structural proteins.
Usage
- Tretiheal Cream 0.05% 20 gm Powerful Retinoid helps clear active pimples, blackheads, and whiteheads while preventing new blemishes from forming deep within the pores.
- This cream improves skin texture and gradually smooths out superficial fine lines by accelerating the removal of older skin cells.
- It helps to fade dark spots, sun spots, and uneven skin coloration by promoting a faster turnaround of surface skin cells.
- This supports the natural renewal of the skin’s surface and helps to improve overall skin appearance and smoothness.
Dosage
- The primary dose is to apply a pea-sized amount on your affected area in the evening or at night once daily.
- Tretiheal Cream 0.05% 20 gm Powerful Retinoid is applied topically.
- It is recommended to consult with your healthcare provider before deciding on a dose as per your skin condition and medical history.
Side effects
Common slide effects are:
- Skin dryness
- Redness and peeling
- Burning or stinging
- Sun sensitivity
- Acne purging
Severe reactions:
- Blistering or crusting
- Severe swelling
Interactions
- Tretiheal Cream 0.05% 20 gm Powerful Retinoid interacts with salicylic acid, benzoyl peroxide, sulfur, resorcinol, and other topical retinoids.
- This cream also interacts with alcohol-based products such as astringents, medicated soaps, and high-alcohol cleansers.
- This cream creates negative actions with photosensitizing drugs such as thiazide diuretics, tetracyclines, or fluoroquinolone antibiotics. This causes severe sunburn.
- Vitamin A supplements can compound side effects.
- Do not apply if you have eczema and rosacea, which may trigger intense irritation and severe flare-ups.
- Do not apply to sunburned or damaged or broken skin.
Pharmacokinetics
Absorption and distribution
- Percutaneous absorption: < 2% to 5%
- Systemic levels: Daily topical application of a 0.05% concentration.
- Tissue binding: Localized mostly in superficial skin layers.
Metabolism and elimination
- Metabolism: Cis-retinoic acid, trans-retinoic acid, and 4-oxoretinoin.
- Half-life: 0.5 to 2 hours.
- Excretion: 24 to 48 hours
Precautions
- Tretiheal Cream 0.05% 20 gm Powerful Retinoid is not recommended during pregnancy or breastfeeding.
- Interaction between alcohol and Tretiheal Cream 0.05% 20 gm is unlikely, as it is a topical product.
- It usually doesn’t affect liver health and rarely interacts with kidney health. But if you have any problem, discuss it with your healthcare provider before using this cream.
- If you are allergic to tretinoin, do not use it.
- Always consult your healthcare provider before applying this cream to your children.
- Older patients may use Tretiheal Cream 0.05% 20 gm medical supervision due to increased susceptibility to its side effects. Caution is advised if patients are above 70 years of age, as they might also have serious health issues or might be on other medications. Your healthcare provider will guide you based on your health condition.
Conclusion
Tretiheal Cream 0.05% 20 gm Powerful Retinoid reduces the extra oil from your skin. It is recommended to apply at night. The amount you need and for how long you need to take it depends on your skin condition. You need to wash and dry the affected area before applying a thin layer of this cream.







Abigail –
Stronger formula that worked well for my skin concerns.