Liofen 10 mg is a muscle-relaxing medicine. It contains baclofen, which is used to treat muscular symptoms such as stiffness, rigidity, and tension. This can occur due to various conditions such as cerebral palsy, multiple sclerosis, motor neuron disease, or injury to the head, brain, or spine. This medicine relieves inflammation and swelling.
Key Features
| About Liofen 10 mg (Baclofen) |
|---|
| Drug Class: Skeletal Muscle Relaxant |
| Subclass: GABA-B Receptor Agonist |
| Active Ingredient: Baclofen |
| Product Details | |
|---|---|
| Composition | Active Ingredient: Baclofen
Inactive Ingredients:
|
| Packaging Type | Blister |
| Pack Size | 10 × 10 |
| Dosage | 10 mg |
| Active Ingredient | Baclofen |
| Shelf Life | 3 Years |
| Usages | Used to reduce muscle stiffness, spasms, and tightness caused by neurological conditions such as spinal cord injury, multiple sclerosis, and other nerve-related disorders. |
How does Liofen 10 mg (baclofen) work?
Liofen 10 mg is a pharmaceutical medicine that is used as a muscle relaxant. It works on the spinal cord as well as the brain to relieve muscle stiffness or spasm by maintaining the strength of the muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. Thus, users relieve pain and improve movement of muscles.
Usage
- Liofen 10 mg is used for the treatment of spasticity (a condition where the muscles contract continuously, causing them to stiffen or tighten) due to various conditions affecting the brain and spinal cord, such as multiple sclerosis, spinal cord injury/diseases, etc.
- This medicine works by inhibiting the release of certain chemicals in the brain and spinal cord.
- Stop interrupted sleep
Dosage
- General dose: Take 3 times in a day.
- Missed dose: Take the missed dose as soon as you remember. Do not take double your dose to make up for the missed dose.
- Overdose: Never take more than the recommended dose. Seek emergency medical treatment in case of an overdose of Liofen 10 mg.
- Below 18 years old: Take advice from your doctor
Side Effects
Common side effects are:
- Drowsiness
- Sleepiness
- Dizziness
- Headache
- Fatigue
- Nausea
- Vomiting
- Dry mouth
- Constipation
- Diarrhea
- Muscle weakness
- Unsteadiness
- Increased need to urinate
Serious side effects are the following:
- Confusion
- Hallucinations
- Severe mood changes
- Breathing difficulties
- Shortness of breath
- Feeling light-headed
- Low blood pressure
- Seizures (fits)
- Vision problems
- Changes in taste
Interactions
- Liofen 10 mg may interact with opioid pain relievers (e.g., morphine, oxycodone, and tramadol), benzodiazepines & anxiety medications (e.g., diazepam, lorazepam, and alprazolam), sleep aids & muscle relaxers (e.g., zolpidem, or other antispasmodics), lithium, and certain anti-inflammatory drugs (NSAIDs) (e.g., Ibuprofen).
- This negatively interacts with alcohol. It may worsen dizziness, fainting, and impaired motor coordination.
Pharmacokinetics
Absorption
- Rate: Rapidly absorbed.
- Peak concentration: 2 – 3 hours.
- Bioavailability: Oral bioavailability.
Distribution
- Volume of distribution: Approx. 0.7 L/kg.
- Plasma protein binding: Approx. 30%
Metabolism
- Hepatic clearance: Approx. 15%
Elimination
- Excreted unchanged by the kidneys: Approx. 70%-80%
- Eliminated in urine: 72 hours of ingestion
Half-Life
- Plasma elimination: 2 to 6 hours
Precautions
- Pregnancy: Liofen 10 mg is not recommended for use during pregnancy.
- Breast-feeding: Liofen 10 mg is not recommended for new mothers. Because these may pass into the breast milk in small amounts, which creates risks for the child/children.
- Abrupt withdrawal: Avoid the discontinuation of Liofen 10 mg without consulting your doctor because it may cause seizures or hallucinations if stopped abruptly.
- Stroke: Occurs due to reduced blood supply to the brain.
- Gastrointestinal disorders: Liofen 10 mg should be used with caution if you have stomach and bowel problems such as any obstruction of your digestive tract or gastric ulcers (sores in the lining of the stomach and intestine). It can make your condition worse.
- Driving or operating machines: Liofen 10 mg may cause blurred vision, dizziness, sleepiness, tiredness, and weakness. Hence, avoid driving or operating machines if you experience such symptoms after taking this medicine.
- Use in children: As per your doctor’s advice
Conclusion
Liofen 10 mg contains baclofen. Liofen 10 mg calms nerve pains through baclofen. It works on the spinal cord and brain. By relaxing tight muscles, it enhances muscle flexibility and coordination, helping patients regain better control and ease in daily movements. This can be taken with or without food. It is recommended to use the lowest effective dose for the shortest duration necessary to manage your symptoms. You should take this medicine consistently as per your doctor’s advice.
ariana foster –
I was having a lot of nighttime spasms but this has truly helped with that!