Baclofen-Neuraxpharm 25 mg tablets are prescription muscle relaxants used to manage muscle spasticity caused by neurological disorders such as multiple sclerosis and spinal cord injuries. By reducing muscle stiffness and involuntary spasms, this medication helps improve mobility, physical function, and overall quality of life when used under medical supervision.
Key Features
| About Baclofen-neuraxpharm 25 mg Tablets |
|---|
| Drug Class: Skeletal Muscle Relaxant |
| Subclass: Gamma-Aminobutyric Acid (GABA-B) Receptor Agonist |
| Product Details | |
|---|---|
| Composition | Active ingredient: Baclofen (25 mg)
Inactive ingredients:
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| Packaging Type | Blister Pack |
| Pack Size | 10 × 10 |
| Dosage | 25 mg |
| Manufacturer | Neurapharma Arzneimittel GmbH |
| Shelf Life | 36 months |
| Usages | Management of muscle spasms and spasticity associated with neurological disorders. |
| Country of Origin | Germany |
How do Baclofen-Neuraxpharm 25 mg tablets work?
Baclofen acts on GABA-B receptors in the spinal cord, suppressing nerve signals that cause excessive muscle contractions, thereby reducing stiffness and spasms.
Usage
- It is used to reduce the symptoms of spasticity.
- To get relief from spasticity due to spinal cord lesions, multiple sclerosis, or other spinal disorders.
DosageÂ
- The starting dose is 25 mg, which can be taken 3 times a day.
- The dosage can be adjusted according to individual requirements.
- It can be taken with or after food to reduce GI upset.
Side-effects
- Drowsiness
- Dizziness
- Weakness
- Nausea
- Fatigue
- Headache
- Hypotension
- Insomnia
- Constipation
- Hallucination
Interactions
- Neurodepressants like alcohol, benzodiazepines, opioids, and antihistamines may increase sedation and respiratory depression risk.
- Antihypertensives may lead to hypotensive effects.
- MAO inhibitors, this may lead to CNS effects or issues.
- Tricyclic antidepressants, this may increase baclofen effects and also may cause muscle hypotonia.
Pharmacokinetics
- Absorption: Rapid oral absorption
- Bioavailability is approx. 70-85% with food.
- Peak plasma concentration: 2–3 hours
- Half-life: 2–6 hours
- Excretion: Primarily through urine
Precautions
- The one who is hypersensitive to baclofen should avoid taking it.
- In the condition of renal impairment, the risk of drug toxicity and seizure disorder may increase.
- Discontinuation can cause hallucination, seizures, rebound, spasticity, and rhabdomyolysis.
- If you are experiencing symptoms impairing alertness, then avoid driving until you know how it affects you.
Conclusion
Baclofen-Neuraxpharm 25 mg tablets are a pharmaceutical drug used as effective relief from muscle spasticity and to improve mobility and comfort in patients with neurological disorders. Baclofen acts on the GABA-B receptors in the spinal cord and inhibits the neurotransmitter release, i.e., glutamate and aspartate, from sensory neurons.
sophie wright –
I tense my muscles too much without realizing but this has helped me a lot