What is Wormchrist 444 mg?
Wormchrist 444 mg is a powerful, broad-spectrum antihelmintic medication formulated to treat and eliminate a wide range of intestinal worm infections in adults. Its key element, Fenbendazole, works by altering parasites’ energy metabolism, resulting in their death and spontaneous ejection from the host.Â
Key Features
| About Wormchrist 444 mg |
|---|
| Drug Class: Antiparasitic |
| Subclass: Benzimidazole derivative |
| Product Details | |
|---|---|
| Composition | Active Ingredient: Fenbendazole
Inactive Ingredients: |
| Packaging Type | Blister |
| Pack Size | 10×10 |
| Dosage | 444 mg |
| Therapeutic Class | Anthelmintic |
| Action Class | Microtubule inhibitor |
| Chemical Class | Benzimidazole derivative |
| Manufacturer | Green Apple Pharmaceuticals Private Limited |
| Shelf Life | 2–3 years from the date of manufacturing |
| Usages | Treatment of common helminth infections |
| Country of Origin | India |
| Storage | Store at 15–30°C, away from direct sunlight and moisture |
How does Wormchrist 444 mg work?
- Preventing microtubule formation: Wormchrist 444Â mg blocks tubulin, a protein required for the formation of microtubules, which is disruptive to cellular activities in parasites.
- Disrupting glucose transport: It blocks the uptake of glucose, starving parasites of nutrients and energy.
- Damaging parasite cells: Wormchrist 444 mg causes cellular injury, ultimately leading to parasite death.
Uses
Wormchrist 444 mg is used to treat infections caused by intestinal worms. Some of the common conditions it addresses include:
- Roundworm Infections (Ascariasis)
- Tapeworm Infections (Taeniasis)
- Hookworm Infections (Ancylostomiasis)
- Whipworm Infections (Trichuriasis)
Dosage
Route of administration: For oral administration only
Standard dosage:
The fenbendazole dosage for cats and dogs is 25 mg per pound (50 mg/kg) daily for three consecutive days
Sheep & Goat: 5 mg/kg body weight as a single dose
Cattle & Horse: 7.5 mg/kg body weight as a single dose
Side effects
Potential side effects of Wormchrist 444 mg are:
- Gastrointestinal issues: Nausea, Vomiting, abdominal pain and diarrhea are seen in animals
- Reduced appetite or lethargy
- Drooling
- Allergic reactions like hives, facial swelling or breathing issues
- Rare cases of pancytopenia
Interactions
- Cimetidine, dexamethasone, and praziquantel enhance plasma levels of Fenbendazole sulfoxide (active metabolite)
- Antacids can reduce absorption
- Carbamazepine and phenytoin may reduce efficacy
- Methotrexate excretion can be decreased due to Fenbendazole
Pharmacokinetics
- Absorption: Fenbendazole is poorly absorbed, absorption increases with fatty meals.
- Metabolism: It undergoes rapid first-pass metabolism to active metabolite Fenbendazole sulfoxide.
- Peak plasma levels reach within 2-5 hours. Half-life is 8-12 hours.
- Elimination: Excreted mainly in feces.
Precautions
- It should not be used for animal infants less than 3 months of age
- Single dose is not effective in dogs and cats; must be treated for at least 3 days
- Monitor your animal during treatment
- Wormchrist 444 mg should be used with caution in animals with liver disease
- Keep out of reach of pets and childrenÂ
Conclusion
Wormchrist 444 mg is a reputable antiparasitic drug that provides effective relief from a variety of intestinal worm infections. Its primary ingredient, Fenbendazole, has been regularly utilized for decades, making it a dependable option for both patients and healthcare practitioners. To ensure safe and successful treatment, always visit a doctor before taking any new drug, and strictly adhere to the given dosage and instructions.
Aiko Kobayashi –
Everything arrived in perfect condition. The team was wonderful.