Iversian 12mg

Iversian 12 mg is an antiparasitic tablet that has ivermectin, a wide range antiparasitic drug. It is utilized to cure numerous parasitic infestations such as strongyloidiasis, onchocerciasis, scabies, and lice infestation. Ivermectin binds to glutamate-gated chloride channels in the nerve and muscle cells of the parasite that results inti paralysis and ultimately death of a parasite.

Key Features

How does Iversian 12 mg Work?

Iversian 12 mg acts by disrupting the parasite’s nervous system, eventually leading to death. It attaches to glutamate-gated chloride channels of the parasite’s nerve and muscle cells, which makes the cell membrane more permeable to chloride ions. Paralysis and death of the parasite result.

Iversian 12 mg with its active ingredient ivermectin acts on and kills parasites from the body. A step-by-step account of how it works is as follows:

• Binding to Glutamate-Gated Chloride Channels: Ivermectin binds to glutamate-gated chloride channels in the nerve and muscle cells of the parasite.
• Increased Permeability: The binding increases cell membrane permeability to chloride ions, causing the cell to take in chloride ions.
• Hyperpolarization: The heightened influx of chloride ions hyperpolarizes the cell membrane, making it challenging for the parasite’s nerves and muscles to function.
• Paralysis and Death: The parasite’s failure to operate adequately causes paralysis and eventually death.
• Elimination: The parasites are then removed from the body by the body’s natural processes of the immune system.

Uses of Iversian 12 mg tablet

• Iversian12 mg is used to treat Strongyloidiasis: Intestinal infection caused by Strongyloides stercoralis
• It is used to treat Onchocerciasis (River Blindness): An infection caused by the Onchocerca volvulus parasite.
• Scabies can be treated by Iversian 12 mg: Skin infection caused due to mite infestation.
• Lice Infestations: Iversian 12 mg oral is a useful alternative when topical treatment is failing or inconvenient.

Dosage

The dose of Iversian 12mg is based on the type and severity of parasitic infection and the age and weight of the patient. It is necessary to adhere to the drug dosage recommended by your doctor or pharmacist.

Some general guidelines:

• For the treatment of Strongyloidiasis, a single dose of 200 mcg/kg body weight, often repeated after two weeks.
• For the treatment of Onchocerciasis treatment, 150 mcg/kg taken once every 6-12 months.
• For the treatment of Scabies, one dose followed by another after 7-14 days.
• To remove head lice, a single dose is possibly repeated in 7 days in lice persist.

Side Effects

• Headache
• Dizziness
• Nausea
• Diarrhea
• Fatigue
• Skin rash

Interactions

• Blood thinners: Ivermectin can enhance the risk of bleeding when co-administered with blood thinners like warfarin.
• Certain antibiotics: Ivermectin can interact with some antibiotics like azithromycin or clarithromycin, perhaps heightening the risk of adverse effects.
• Anticonvulsants: Ivermectin can interact with anticonvulsants like valproic acid, perhaps altering its effectiveness or heightening the risk of adverse effects.
• Other drugs: Ivermectin has the potential to interact with other drugs, such as some antifungals, antivirals, and anti-anxiety drugs.

Pharmacokinetics

• Absorption: Absorption of ivermectin is slow following oral intake, with the peak plasma levels being achieved within 4-5 hours.
• Distribution: Ivermectin is extensively distributed in the body with maximum concentrations in the liver and adipose tissues.
• Metabolism: Ivermectin is heavily metabolized in the liver by the cytochrome P450 enzyme system, mainly.
• Elimination: Ivermectin is mainly excreted in the feces and to a lesser extent in the urine. The half-life of ivermectin is around 18 hours.

Pharmacokinetic Factors Influencing Ivermectin

• Food: Food influences the absorption of ivermectin and may enhance its bioavailability.
• Age: The pharmacokinetics of ivermectin can be influenced by age, with elderly subjects possibly showing drug clearance changes.
• Liver function: Ivermectin is widely metabolized by the liver, therefore liver impairment might influence its pharmacokinetics.
• Other health conditions: Some health states, like renal disease, can influence the elimination of ivermectin.

Precautions

• Inform your doctor or healthcare professional prior about your medical conditions like heart, kidney or Liver condition.
• Iversian 12 mg may interact with other medications, including warfarin, barbiturates, benzodiazepines, and anti-seizure drugs.
• Avoid alcohol while taking Iversian tablet.

Conclusion

Iversian 12 mg is a potent antiparasitic drug employed to treat a range of parasitic infections like Strongyloidiasis, Onchocerciasis, and Scabies. It works by paralyzing and killing parasites, providing rapid symptom relief

relief and effective Although generally well tolerated, it can produce side effects and interact with other drugs. Always ask your healthcare provider or pharmacist for advice before taking Iversian 12 mg.

References

https://pubmed.ncbi.nlm.nih.gov/35225114/

https://pubchem.ncbi.nlm.nih.gov/compound/6427057

FAQ

1) What is Iversian 12 mg used for?

Iversian 12 mg is employed in the treatment of different parasitic infections such as strongyloidiasis, onchocerciasis, scabies, and infestations by lice.

2) How does Iversian 12 mg work?

Iversian 12 mg functions by disrupting the parasite’s nervous system, leading to their eventual death.

3) What are the frequent side effects of Iversian 12 mg?

Frequent side effects can be headache, dizziness, nausea, diarrhea, weakness, and rash.

4) What is the dosage of Iversian 12 mg?

The dosage of Iversian 12 mg varies depending on the type and severity of the infection.

5) Is Iversian 12 mg safe?

Iversian 12 mg is generally safe but it is recommended to use after consulting a doctor or medical professional.