Ivermectine 12mg

Ivermectin consists of Ivermectin which has anti-inflammatory, anti-viral, anti-bacterial, and anti-tumor effects. In the late 1960s, Satoshi Ōmura and William Campbell grew bacteria from soil samples. which they took from a Japanese golf course. They found a new species, Streptomyces avermectinius, a soil actinomycete that made the active ingredient avermectin. Ivermectin is a man-made version of a substance called avermectin. It is an antiparasitic macrocyclic lactone that works against a wide range of parasites. It works against parasites and has a structure like a macrolide. 

Ivermectin is available as a tablet and is commonly administered orally. Ivermectin is the generic name of the drug, commonly used for parasitic infections in various life forms. It is classified as an anthelmintic drug used to kill or remove parasitic worms and other parasites. Parasitic skin infection products are also available in a topical form. It essentially binds to those glutamate-gated chloride ion channels found in the nervous system of the parasite, enhancing chloride ion permeability causes the paralysis and death of the parasite. 

What are the uses of Ivermectine 12mg?

1. Onchocerciasis (river blindness): This results from an infection caused by the nematode Onchocerca volvulus.
2. Strongyloidiasis is caused by parasitic worms which induct Strongyloides stercoralis infection. 
3. Scabies is an infestation of the skin caused by mites (Sarcoptes scabiei).
4. Head lice are combated and destroyed.
5. Lymphatic filariasis is an infection caused by Wuchereria bancrofti or Brugia malayi.
6. Rosacea is sometimes used for managing the inflammatory lesions and skin irritation associated with this condition. 
7. Crusted Scabies is an intense form of scabies that mainly appear in immunocompromised people.
8. Ivermectin was considered for use in COVID-19 treatment. Nevertheless, leading health authorities such as the WHO and the FDA have not backed its use for coronavirus due to a lack of engaging evidence. 

How does Ivermectine 12mg work?

Ivermectine 12mg works by targeting the nervous system of parasites, leading to their paralysis and death. Below is a detailed explanation of its mechanism:

• Binding to Chloride Channels

Ivermectin binds specifically to one type of channel in the nerve and muscle cells, namely the glutamate-gated chloride channels, important for nerve impulse transmission in parasites.

• Increased Chloride Ion Influx

Upon binding, the influx of chloride ions into the cells of the parasite increases. The perturbation necessary for nerve signaling is altered. Paralysis and Death:

• Hyperpolarization

The parasite’s nerve and muscle cells do not function well and cannot provide proper signaling. which leads to their paralysis. The parasite becomes immobile and unable to feed or reproduce. Over time, the parasite dies due to its inability to function and die. 

• Safe for Human

Ivermectin does not affect human nerves and muscles significantly because human nerve and muscle cells do not have glutamate-gated chloride channels. The drug has a low affinity for similar receptors (e.g., GABA receptors) in humans, and it does not cross the blood-brain barrier in healthy individuals.

Why is it important to complete the Ivermectine 12mg treatment?

Completing the full course of treatment prescribed for Ivermectine 12mg (ivermectin) ensures the following: 

1. Total eradication of the parasites and prevents reinfection as well as resistance to the drug. 
2. If the treatment is not fully complete, there could be survival of other parasites, leading to the resurgence of the infection in this case, possibly resulting in the adaptation of these parasites to be less responsive to future treatments. 
3. One would complete a treatment to lessen the chances of complications due to parasitic infections, especially the allergic reactions resulting from the release of toxins upon the death of the parasite. 
4. Staying to the prescribed course of treatment is vital in achieving the desired therapeutic effect and thus resolving the infection. 

Side effects of Ivermectine 12mg

Common Side Effects:

1. Gastrointestinal Issues:

   • Nausea
   • Vomiting
   • Diarrhea
   • Abdominal pain

2. Neurological Symptoms:

   • Dizziness
   • Headache
   • Fatigue or drowsiness

3. Skin Reactions:

   • Itching
   • Rash
   • Dry skin

Less Common but Serious Side Effects:

1. Mazzotti Reaction:

   • This occurs during treatment for onchocerciasis (river blindness) and is caused by the immune system reacting to dying microfilariae (parasite larvae).
   • Symptoms include:
     • Fever
     • Swelling
     • Intense itching
     • Joint or muscle pain
     • Enlarged lymph nodes

2. Allergic Reactions:

   • Rare but may include:
     • Hives
     • Swelling of the face, tongue, or throat
     • Difficulty breathing

3. Low Blood Pressure (Hypotension):

   • May cause lightheadedness or fainting in some individuals.

4. Neurological Symptoms (Rare):

   • Tremors
   • Confusion
   • Seizures
   • Loss of coordination

Overdosage signs of Ivermectine 12mg

Overdosage of Ivermectine 12mg (ivermectin) can lead to toxic effects, primarily affecting the nervous system. 

Common signs 

• Confusion
• Drowsiness
• Dizziness
• Tremors
• Seizures
• Nausea
• Vomiting
• Abdominal pain

Severe cases cause: 

• Loss of coordination
• Difficulty walking
• Coma. 

An overdose requires immediate medical attention, as it can be life-threatening, with treatment focusing on supportive care to manage symptoms and prevent complications.

What to do in case of an overdose of Ivermectine 12mg?

In the case of an overdose of Ivermectine 12mg (ivermectin), immediate medical attention is crucial to prevent severe complications. Here are the steps to take:

1. Seek Emergency Medical Help:

Contact emergency services or go to the nearest hospital immediately. Overdose can lead to life-threatening symptoms, such as seizures, respiratory depression, or coma.

2. Call a Poison Control Center:

If available, contact a poison control center for guidance on managing the situation before reaching a medical facility.

3. Do Not Induce Vomiting:

Unless directed by a healthcare professional, avoid inducing vomiting, as this can worsen the situation.

4. Bring the Medication:

If possible, take the packaging or prescription of Ivermectine 12mg with you to the hospital to help healthcare professionals assess the situation and provide targeted treatment.

Precautions to take when consuming Ivermectine 12mg

Follow Prescribed Dosage

• Always take Ivermectine 12mg exactly as prescribed by your doctor, based on your weight, age, and condition.
• Do not exceed the recommended dose to avoid side effects or overdose.

Take on an Empty Stomach

• Ivermectine 12mg is typically most effective when taken on an empty stomach with water, unless your doctor advises otherwise.

Avoid Self-Medication

• Do not take Ivermectine 12mg without consulting a healthcare professional, as incorrect use can lead to complications or ineffective treatment.

Inform Your Doctor of Medical History

• Disclose any history of liver or kidney disease, weakened immune system, or neurological conditions before starting treatment.
• Let your doctor know if you have any allergies, especially to ivermectin or similar medications.

Check for Drug Interactions

• Inform your doctor about all medications, supplements, or herbal products you are taking, as Ivermectine 12mg may interact with blood thinners, anticonvulsants, or sedatives.

Pregnancy and Breastfeeding

• Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Ivermectine 12mg is generally not recommended during pregnancy unless the benefits outweigh the risks.

Monitor Side Effects

• Watch for signs of allergic reactions, such as swelling, hives, or difficulty breathing.
• Report severe side effects like dizziness, confusion, seizures, or vision changes immediately.

Avoid Alcohol

Avoid consuming alcohol while taking Ivermectine 12mg, as it may increase the risk of side effects like dizziness or nausea.

Use with Caution in Scabies or Onchocerciasis

• In conditions like scabies or onchocerciasis, be prepared for temporary worsening of symptoms (e.g., itching, swelling) as parasites die off.

Keep Hydrated

• Stay well-hydrated to help your body manage any potential side effects, such as dizziness or low blood pressure.

Storage

• Store the medication at room temperature, away from direct sunlight and moisture, and out of reach of children.

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1. Ivercares.com guarantees that you get genuine and high-quality Ivermectine 12mg from a reputable source thus the reduced risk of counterfeit or substandard products.
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4. Purchasing online is also more private than buying medicines from a medical store 
5. Most people have had good experiences with it and it has good customer reviews. They are completely satisfied with the medications and the service that we provide. 

FAQ

• Where to buy Ivermectine 12mg online in USA?

The most suitable online platform to buy Ivermectine 12mg in USA is ivercares.com  because the medications are from legitimate sources and manufacturers. The medicines are FDA-approved and generic which saves money and are as efficient as the branded ones.  

• How should I take Ivermectine 12mg?

Ivermectine 12mg is typically taken as a single dose or a series of doses, depending on the infection being treated, the severity of the condition, age, underlying conditions and other medications that you take. 

• Can I take Ivermectine 12mg if I’m pregnant or breastfeeding?

Ivermectine 12mg is generally not recommended for use during pregnancy as it can pose risks to the developing fetus and might enter the milk and affect the feeding child. 

• Can I buy Ivermectine 12mg without a prescription?

No, Ivermectine 12mg (ivermectin) is a prescription medication, and it is illegal to purchase it without a valid prescription in most countries, including the USA. You must consult a healthcare provider to get a prescription before you buy Ivermectine 12mg, either in-person or from a verified online pharmacy.

• Are there any drug interactions I should be aware of with Ivermectine 12mg?

Yes, Ivermectine 12mg may interact with other medications. It can have enhanced effects when taken with drugs like certain anticonvulsants or sedatives, which affect the nervous system.