Iversafe  12mg is a generic composition of Ivermectin which is well known worldwide as a broad spectrum antiparasitic drug for human and veterinary use. It is an avermectin drug (drugs derived from fermentation products of Streptomyces avermitilis). Ivermectin is indicated in the treatment of several parasitic infestations, including but not limited to onchocerciasis (river blindness), strongyloidiasis, scabies, and other infections caused by parasitic worms. It has also gained interest in recent years because of its possible antiviral activity and anti-inflammatory properties.

The Discovery of Ivermectin was discovered in the 1970s by Satoshi Ōmura and William C. Campbell, who were awarded the 2015 Nobel Prize in Physiology or Medicine for their contributions.It was first used to treat parasitic infections in animals.It was also approved for treating onchocerciasis (river blindness) in humans under the WHO’s Mass Drug Administration programs.

For the expanded use, it has been used to treat other parasitic infections like strongyloidiasis, scabies, and lice. The recent research has been studied for potential use in viral infections, including COVID-19, but results remain inconclusive. 

It Binds to glutamate-gated chloride channels in the nerve and muscle cells of parasites, increasing chloride ion permeability which causes paralysis and death of the parasite.It also has some effect on gamma-aminobutyric acid (GABA) receptors, but it does not cross the human blood-brain barrier in normal doses. The Antiparasitic Activity: Effective against nematodes (roundworms), arthropods (lice, mites, and scabies), and some filarial worms.The Potential Antiviral & Anti-inflammatory Properties: Suggested to inhibit viral replication in some lab studies, though clinical efficacy remains debated. 

What are the uses of Iversafe  12mg 

Iversafe  12 mg is for Ivermectin treatment for human parasitic infections. Onchocerciasis and Strongyloidiasis, both worm-borne infections, are treated by it. In addition, it is also credited to largely parasitic diseases like scabies, head lice, and similar ectoparasites where it paralyzes and kills these parasites. In some cases, Iversafe  12mg is utilized for managing filariasis, as well as transgression indications for treatment of rosacea and cutaneous larva migrans. It has been researched concerning its possible potentiality as an antiviral agent; however, the efficacy of Iversafe  against viral disease has not yet established against viral hosts, including COVID-19. The drug will mainly be utilized in tropical and subtropical regions that are often hot and where parasitic infections are profuse, making a significant contribution to the global health programs on the neglected tropical diseases control initiative.

How does the Iversafe  12mg  tablet work?

Iversafe  ideally performs the targeting and disrupting the entire nervous systems of the parasites. This destruction eventually leads to their paralysis and eventually leads to death. Its active ingredient, Ivermectin, binds to glutamate-gated chloride channels present in the nerve and muscle cells of parasites, increasing the influx of chloride ions. This causes hyperpolarization, which results in paralysis and the inability of the parasites to feed or reproduce. Additionally, Ivermectin has some effect on gamma-aminobutyric acid (GABA) receptors, but since it does not significantly cross the human blood-brain barrier at normal doses, it remains safe for human use. The drug is effective against intestinal worms, lice, mites, and other parasitic infections, making it a crucial medication for treating various neglected tropical diseases.

Why is it important to complete the Iversafe  12mg treatment?

The entire course of treatment with Iversafe  12mg (Ivermectin) must be completed for full eradication of the parasitic organisms and to prevent the possibility of drug resistance. Ivermectin binds to the glutamate-gated chloride channels resulting in hyperpolarization of nerve and muscle cells and paralysis and death of the parasite. Some parasites may survive and acquire some mechanisms of adaptive resistance when treatment is stopped before completion making it less effective in future infections. Besides, it might also allow remaining parasites to continue developing their reproductive activities, leading to reinfestation or persistence of infection. Such situations are especially relevant to onchocerciasis and strongyloidiasis, where at times incomplete treatment may fail to clear infected individuals of microfilariae, prolonging the morbidity, increasing the chances of transmission, and hence the circulation of infection within any host or community. It implies that appropriate completion of the prescribed course ensures effective clearing of parasites from the host, reduces the occurrence of cases, and prevents transmission of the infection within the host and possible spillover into the community.

Side effects 

Common Side Effects

• Headache
• Dizziness
• Nausea and vomiting
• Diarrhea
• Fatigue and weakness
• Muscle pain (myalgia)

Less Common but Serious Side Effects

• Low blood pressure (hypotension)
• Swelling of the face, hands, or feet (edema)
• Skin rash, itching, or hives (allergic reactions)
• Fast or irregular heartbeat (tachycardia or arrhythmia)
• Blurred vision or eye pain

Rare but Severe Side Effects

• Neurological effects (dizziness, confusion, seizures, loss of coordination)
• Severe allergic reactions (anaphylaxis)
• Liver dysfunction (elevated liver enzymes, jaundice)
• Swelling of lymph nodes (lymphadenopathy)

Special Considerations

• Patients with onchocerciasis (river blindness) may experience Mazzotti reaction, which includes fever, rash, eye inflammation, and joint pain due to the immune response against dying parasites.
• People with weakened immune systems (e.g., HIV/AIDS) may experience prolonged or worsened side effects.

Overdosage signs of Iversafe  12mg

Major neurological, gastroenterological, and cardiovascular complications follow an overdose of Ivermectin through Iversafe  12 mg in the human body by hyperchloridemia influxes within the nervous system. Some of the early signs may include, but are by no means limited to nausea, vomiting, abdominal pain, and dizziness, while after this more severe signs of overdose such as confusion, tremors, seizures, and coordination losses (ataxia) follow. Further along the spectrum, the patient may present with hypotension (i.e., low blood pressure), respiratory distress, tachycardia (i.e., increased heartbeat), and even possible coma due to the toxic effects of too much binding of Ivermectin through the GABA-gated chloride channels in conditions of the central nervous system. It can also cause blurred vision, mydriasis, and liver impairment in some overdose cases. Ivermectin has no specific antidote for an overdose, and the management involves symptomatic care, supportive measures such as gastric lavage, activated charcoal, intravenous fluids, and possibly respiratory support. Immediate medical intervention is necessary and may be life-saving against complications of overdose.

What to do in case of an overdose of Iversafe  12mg?

If there is an overdose of Iversafe  12mg (Ivermectin), the patient must receive medical attention as soon as possible to prevent serious complications. The affected person should be rushed to the nearest hospital or emergency center. Gastrointestinal irrigation (stomach pumping) and charcoal will limit drug absorption, provided the overdose was recent. Supportive care is vital, and this may include IV fluids to standardize blood pressure, oxygenation assistance for those with labored breathing, and perhaps anti-seizure medications in cases of neurological symptoms manifesting as tremors or seizures. The monitoring of vital signs, including heart rate, blood pressure, and neurological status, becomes crucial in determining the level of toxicity. There is no antidote available for Ivermectin overdose, so treatment is primarily symptomatic and supportive. In cases of severe adverse effects, such as respiratory depression or coma, mechanical ventilation may be required. Medical intervention must be sought immediately as it greatly increases the chances of recovery and decreases the risk of complications that may be life-threatening.

Precautions to take when consuming Iversafe  12mg

When consuming Imectin 12mg (Ivermectin), it is important to take certain precautions to ensure safety and effectiveness. The medication should be taken exactly as prescribed by a healthcare professional, preferably on an empty stomach with water for optimal absorption. Patients with a history of liver disease, kidney disorders, or neurological conditions should inform their doctor before using the drug, as it may require dosage adjustments. Alcohol consumption should be avoided, as it may increase the risk of dizziness, drowsiness, and liver toxicity. Pregnant or breastfeeding women should consult a doctor before use, as the safety of Ivermectin in such cases is not fully established. Individuals with severe parasitic infections, such as onchocerciasis, should be monitored for potential allergic reactions or inflammatory responses like the Mazzotti reaction, which can cause fever, rash, and eye swelling. Additionally, patients should avoid driving or operating heavy machinery if they experience drowsiness, dizziness, or vision disturbances after taking the medication. If any severe side effects or allergic reactions occur, immediate medical attention is necessary to prevent complications.

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Buying Iversafe  12mg from Ivercares.com offers several advantages, ensuring a safe, reliable, and hassle-free experience. We guarantee authentic and high-quality medications sourced from licensed and certified manufacturers, eliminating the risk of counterfeit products. Our platform is designed for secure transactions, offering multiple payment options, including credit/debit cards and other trusted methods, to ensure a smooth purchasing process.

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Ivercares.com also provides valuable health information, expert consultations, and prescription assistance, making it more than just an online pharmacy. By choosing us, you ensure safety, affordability, and convenience, making it the best place to buy Iversafe  12mg with confidence. 

FAQ

1. Where to buy Iversafe  12mg online in USA?

Ivercares.com is a suitable platform for Iversafe  12mg. We offer secure online ordering, fast shipping across the US, and competitive pricing to ensure a hassle-free experience. Our products are sourced from licensed manufacturers, ensuring high quality and safety. 

2. What should I do if I miss a dose of Iversafe  12mg?

If you miss a dose, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

3. Is Iversafe  12mg safe for children?

Iversafe  12mg is generally not recommended for children under 15 kg (33 lbs). Always consult a pediatrician before administering this medication to children.

4. How should I store Iversafe  12mg?

Store Iversafe  12mg at room temperature (20-25°C / 68-77°F), away from direct sunlight, moisture, and heat. Keep it out of reach of children and pets.

5. Can I take Iversafe  12mg with other medications?

You should inform your doctor about all the medications you are taking, including antibiotics, antifungals, blood thinners, and sedatives, as Ivermectin may interact with certain drugs and affect its effectiveness.