Spimect 12mg is a pharmaceutical formulation containing 12 milligrams of ivermectin, an antiparasitic agent used to treat various parasitic infections in humans.
Ivermectin is a semisynthetic derivative of avermectins, which are macrocyclic lactone compounds produced by the soil bacterium Streptomyces avermitilis. It is a mixture of two homologues, with the chemical formula C<sub>48</sub>H<sub>74</sub>O<sub>14</sub>. Ivermectin is characterized by its high lipid solubility, facilitating its distribution within the body.
Ivermectin was discovered in the late 1970s and originally was employed in veterinary medicine to treat parasitic infections in animals. Its efficacy and safety led to a 1980s approval for human use, which significantly helped the treatment of onchocerciasis (river blindness) and lymphatic filariasis.
Spimect 12mg is often indicated in the treatment of various parasitic infections including those of the intestinal tract, skin, and eye. Its efficacy and safety help it to control and eliminate parasitic diseases better.
Ivermectin is considered to be very safe in humans since glutamate-gated chloride channels are absent in human cells, and ivermectin has poor penetration across the human blood-brain barrier.
What are the uses of Spimect 12mg?
Spimect 12mg is prescribed for the following diseases:
- Intestinal and Tissue Parasitic Infections
- Strongyloidiasis is a gastrointestinal roundworm infestation caused by Strongyloides stercoralis.
- Onchocerciasis (river blindness) is an infection caused by the filarial worm Onchocerca volvulus, carried by black flies, resulting in intense pruritus and visual impairments.
- Lymphatic filariasis is an infection transmitted by mosquitoes, leading to swelling of limbs and other body parts.
2. Dermatological and External Parasitic Infestations
- Sarcoptes scabiei mites cause dermatological conditions. It results in severe pruritus and rash.
- Head Lice is an unapproved application for eradicating lice infestations.
3. Dermatological Applications
Rosacea is a mite-associated disease. It is utilized in instances associated with Demodex mites. It alleviates irritation and skin lesions.
4. Novel and Off-Label Applications
- Despite research on ivermectin’s antiviral properties, it has largely not received acceptance from health organizations for the treatment of COVID-19.
- In certain locations, it manifests as trichuriasis (whipworm infection) and ascariasis (roundworm infection).
How does Spimect 12mg work?
Spimect works in the following ways:
1. Binds glutamate-gated chloride ion channels
Ivermectin exerts its antiparasitic effect by binding to glutamate-gated chloride ion channels, which block the nerve and muscle signals of parasites.
2. Paralyzes and death of parasites
This binding increases permeability to chloride through the cell membrane, resulting in paralysis and death of the parasite.
3. Administration and elimination
When administered by mouth, Ivermectin enters the bloodstream and reaches peak plasma concentrations after about 4 hours; it is metabolized in the liver and has a half-life of about 12 to 16 hours. The major route of elimination is through the feces.
Why is it important to complete the Spimect 12mg treatment?
It is important to complete the course of Spimect 12mg for the following reasons:
1. Complete elimination of parasites
Sometimes you might feel better after taking the treatment for some time. However, it is important to complete the treatment only after a doctor tells you to do so. This ensures that the infection-causing parasites are destroyed and do not come again.
2. Avoid the parasites from becoming resistant
Some parasites may be able to live and build resistance to the medicine if you discontinue treatment before the recommended duration. The resistant parasites would be difficult to kill because they won’t work even when the treatment has changed.
The doctor will do various tests like Urea Breath Test (UBT), stool antigen test, and endoscopy with biopsy which will help the PCP to decide if the parasites are completely eliminated or not.
Side Effects of Spimect 12mg
Common side effects include
- Dizziness
- Nausea
- Headache
Severe symptoms are
- Vision problems
- Confusion
- Extreme weakness
If any medications persist seek medical attention. The severe symptoms require immediate medical intervention.
Overdosage signs of Spimect 12mg
Common signs and symptoms of overdosage are listed below.
Spimect 12 mg (Ivermectin overdosage) can cause serious side effects. Certain side effects are:
- Neurological Symptoms like dizziness, confusion, tremors, seizures, or coma
- Gastrointestinal Symptoms present as nausea, vomiting, diarrhea, or abdominal pain
- Cardiovascular Symptoms may include low blood pressure, increased heart rate, or disturbances of heart rhythm
- Respiratory Symptoms comprise shortness of breath or respiratory depression
- Visual and dermatological symptoms are blurred vision, rash, or swelling.
What to do in case of an overdose of Spimect 12mg?
If you or someone else has taken too much Spimect 12 mg (Ivermectin), immediate medical attention is crucial to prevent serious complications. Follow these steps to ensure the best possible outcome:
1. Call Emergency Services Immediately
Dial 911 or your local emergency number if the person is unresponsive, having seizures, or struggling to breathe. Prompt medical intervention can cause as little damage as possible. .
2. Contact a Poison Control Center
In many countries, Poison Control Centers provide expert advice on handling overdoses. Call them for specific guidance based on the situation.
3. Do Not Induce Vomiting
Avoid making the person vomit unless explicitly instructed by a medical professional, as this could worsen the condition.
4. Help in Immediate Supportive Care
The entire focus is on keeping the individual calm and in a position that will be comfortable for them to avoid further distress. If low blood pressure is noted, the person should be laid flat with legs elevated to facilitate circulation. While awake and not actively vomiting, give the person small sips of water to prevent dehydration.
5. Seek Hospital Treatment
Medical professionals may administer activated charcoal to limit absorption if the overdose is recent.
IV fluids, oxygen, and medications may be given to stabilize vital signs and manage symptoms.\
Precautions to take when consuming Spimect 12mg
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Take as Prescribed
Always follow your doctor’s dosage instructions. Do not self-medicate or exceed the recommended dose.
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Consume on an Empty Stomach
Take Spimect 12 mg with a full glass of water on an empty stomach, at least one hour before or two hours after meals, for better absorption.
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Avoid Alcohol
Alcohol may increase the risk of side effects such as dizziness, nausea, and liver strain.
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Monitor for Allergic Reactions
If you experience symptoms like rash, itching, swelling, or breathing difficulties, seek medical help immediately.
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Inform Your Doctor About Medical Conditions
If you have liver disease, kidney disease, asthma, or a weakened immune system, consult your doctor before taking Spimect.
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Be Cautious with Other Medications
Inform your doctor about any other medications, supplements, or herbal remedies you are taking to avoid harmful drug interactions.
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Pregnancy and Breastfeeding
Pregnant or breastfeeding women should use Spimect only if prescribed by a doctor, as its safety in these conditions is not well established.
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Avoid Driving or Operating Machinery
Ivermectin can cause dizziness and drowsiness, which may affect concentration and coordination.
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Regular Medical Monitoring
If taking Ivermectin for prolonged treatment, regular check-ups may be necessary to monitor its effects on your health.
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- Ivercares.org is an accepted online pharmacy with all pharma licenses and accreditations.
- We have many online reviews and are known for our good reputation.
- We do not dispense drugs without prescription requirements.
- We furnish all the manufacturer details such as the manufacturer of Spimect 12mg and the origin country.
- The URL has “https” and there is a padlock, that proves that the financial transaction are safe.
FAQ
- How does Spimect 12 mg affect the brain?
It is important to take the right dose of Spimect after complete guidance from your PCP; otherwise, it can affect the brain and lead to tremors, myoclonus, seizures, encephalopathy, and even coma.
- Where can I purchase Spimect 12 mg online in the United States?
The most appropriate platform to purchase Spimect 6mg in the USA is ivercares.com, as it is a reputable and accredited pharmacy. It is an online medical shop that is well stocked and with FDA-approved generic medicines that are cheaper than branded medicines but have the same efficacy.
- Can I take Spimect 12 mg with other medications?
Blood-thinning medications, immunosuppressants, and certain antibiotics may interact with Ivermectin. Therefore, it is important to consult with your doctor before taking Spimect who will guide you with a treatment based on the medications you take, your age, and your underlying conditions.
- How long does Spimect 12 mg take to work?
The effects usually begin within a few hours to days, depending on the condition being treated. Full parasite clearance may take a few weeks.
- Is Spimect 12 mg safe for children?
Ivermectin is generally not recommended for children weighing less than 15 kg (33 lbs) unless prescribed by a doctor.
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