Iverheal 12mg

Iverheal 12 mg is an antiparasitic drug that consisting of ivermectin. It can be used to treat various parasitic diseases, including scabies, lice infestations, intestinal strongyloidiasis, and onchocerciasis. It paralyses and kills parasites, giving instant relief for such conditions.

Key Features

How Does Iverheal 12mg Work?

• In invertebrate nerve and muscle cells, it binds to glutamate-gated chloride ion channels, increasing cell membrane permeability to chloride ions.
• Inducing the hyperpolarization of the nerve and muscle cell, leading to paralysis and death of parasite.
• Paralyzing parasites: The active component, Ivermectin, binds to certain receptors in the nervous system of the parasite and in muscle cells, resulting in an influx of chloride ions.
• Killing parasites: This increases permeability, hyperpolarizes nerve and muscle cells, and finally leads to paralysis and death of the parasite.
• Targeting GABA-mediated neurotransmission: Ivermectin is also an agonist of the neurotransmitter gamma-aminobutyric acid (GABA) and disrupts GABA-mediated central nervous system (CNS) neurosynaptic transmission in parasites.

This action mechanism makes Iverheal 12 mg effective against a broad spectrum of parasites, such as:

• Nematodes (roundworms)
• Ectoparasites (mites, lice)

Targeting the nervous system and muscle cells of the parasite, Iverheal 12 mg brings fast relief from parasitic infections.

Side Effects

• Gastrointestinal Symptoms: Diarrhea, nausea, vomiting, stomach upset
• Neurological Symptoms: Dizziness, drowsiness, shakiness
• Skin Reactions: Skin rash, pruritus
• Other Effects: Fatigue, loss of energy, loss of appetite

Usages OF Iverheal 12mg Tablets

Iverheal 12 mg is used to treat various Parasitic Infections like:

• Intestinal strongyloidiasis caused by the Strongyloides stercoralis parasite.
• Onchocerciasis caused by the Onchocerca volvulus worm, that leads to serious skin and eye lesions.
• Scabies caused by the Sarcoptes scabiei mite, that leads to itching and skin rashes.
• Iverheal 12 mg is also effective against lice infestations.

Dosage

The dose of Iverheal 12 mg depends on the condition and weight of the patient. It is normally administered as a single dose once on an empty stomach with water, at least 1 hour prior to a meal.

• For Onchocerciasis, a single dose of 150 mcg/kg body weight can be taken orally on an empty stomach.
• For Strongyloidiasis, a single dose of 200 mcg/kg body weight can be taken orally on an empty stomach.
• For Scabies, a single dose of 200 mcg/ kg body weight can be taken orally on an empty stomach. A second dose can be taken after 1-2 weeks.

Interaction of Iverheal 12 mg

Ivermectin can interact with other drugs, which include:

• Blood thinners: Iverheal can increase the chances of bleeding when combined with blood thinners like warfarin.
• Certain antibiotics: Iverheal can interact with some antibiotics, like azithromycin or clarithromycin, which can enhance the likelihood of side effects.
• Anticonvulsants: Iverheal can interact with anticonvulsants, like valproic acid, which can influence the effectiveness and safety of both drugs.

Pharmacokinetics of Iverheal 12mg 

Iverheal 12 mg is slowly absorbed when taken orally, with plasma concentrations peaking at 4-5 hours. It is maximally metabolized in the liver and excreted mainly in the feces.

• It Slow absorption of Ivermectin following oral intake, with maximum plasma levels being attained in 4-5 hours.
• It is Highly distributed in the body, with a high volume of distribution. It is highly lipophilic and accumulates in fatty tissues.
• It is Metabolized by the cytochrome P450 enzymes in the liver, mainly CYP3A4.
• It is Mainly excreted in the feces, with minimal excretion in the urine.

Safety Concern

• Notify your healthcare provider: Notify your healthcare provider about all drugs you take, both prescription and over-the-counter drugs, vitamins, and herbal remedies.
• Watch for side effects: Watch for your side effects and report any severe or ongoing side effects to your healthcare provider.
• Dose adjustment: Your healthcare provider may have to change the dose of ivermectin or other drugs to avoid interactions.

Clinical Trials

Iverheal 12 mg has been thoroughly tested in clinical trials, showing its safety and effectiveness in the treatment of many parasitic infections, including:

• Strongyloidiasis: Ivermectin is found to be very effective for the treatment of strongyloidiasis, a parasitic infestation due to the Strongyloides, stercoralis worm.
• Scabies: Ivermectin has also been employed to cure scabies, a dermatitis caused by the Sarcoptes scabiei

Precautions 

Prior to taking Iverheal 12 mg, consult your healthcare provider regarding:

• Please check prior Medical history: Some medical conditions, like liver disease or seizures, can influence the safety and effectiveness of ivermectin.
• Look whether the drug shows any interaction with other Medications: Ivermectin interacts with other medications, for example, blood thinners or some antibiotics.
• Is it safe to use in Pregnancy and lactation: Use of ivermectin during pregnancy and lactation is cautioned as its safety under these conditions is not clearly established.

Conclusion

Iverheal 12 mg is a highly effective antiparasitic drug used to treat many parasitic infections, such as onchocerciasis, strongyloidiasis, scabies, and lice infestation. Knowing the precautions and possible interactions, you can utilize Iverheal 12 mg efficiently and safely. Get personalized advice and monitoring from your healthcare provider. With correct usage, Iverheal 12 mg can give quick relief against parasitic infections and enhance your overall health.

References

https://pubchem.ncbi.nlm.nih.gov/compound/Ivermectin

https://pmc.ncbi.nlm.nih.gov/articles/PMC8354388/

FAQs

1.What is Iverheal 12 mg used for?

Iverheal is used to treat various parasitic infections, including intestinal strongyloidiasis, onchocerciasis, scabies, and lice infestations.

2.How does Iverheal 12 mg work?

Iverheal 12 mg works by paralyzing and killing parasites, helping the body to eliminate them naturally.

3.Is Iverheal 12 mg safe for everyone?

Yes, Iverheal is safe for everyone but can use only after consulting your doctor.

4.Does Iverheal 12 mg interacts with other drugs?

Iverheal 12 mg interacts with blood thinners, benzodiazepines and other medications.

5.What are the common side effects of Iverheal 12 mg?

Common side effects include diarrhea, nausea, dizziness, itching, and fast heart rate.