Cephadex 250 Mg

What is Cephadex 250 mg (Cephalexin)?

Cephadex 250 mg is a cephalosporin antibiotic containing Cephalexin, used to treat bacterial infections. Cephalexin is a first-generation cephalosporin antibiotic. It represents a number of medicament treatments against bacterial infections. This is a broad-spectrum antibiotic efficient against Gram-positive and partially Gram-negative bacteria.

How does Cephadex 250 mg (Cephalexin) work?

Cephalexin exerts its bactericidal action by inhibiting cell wall synthesis, which ultimately results in cell lysis. It is effective against gram-positive and some gram-negative bacteria.

• Inhibits cell wall synthesis: Cephalexin binds to penicillin-binding proteins in bacterial cell walls.
• Inhibits peptidoglycan synthesis: This binding inhibits the synthesis of peptidoglycan, a crucial component of bacterial cell walls.
• Weakened cell wall: It is unable to withstand the osmotic pressure.

Uses of Cephadex 250 mg (Cephalexin)

Treats bacterial infections associated: –

• Skin infections include cellulitis and impetigo.
• Respiratory tract infections include pneumonia and bronchitis.
• Urinary tract infections (UTIs)
• Otitis media, or ear infections
• Bone infections: osteomyelitis

Dosage of Cephadex 250 mg (Cephalexin)

250 mg every 6-12 hours, check physician’s order

Different Strength of Cephadex

• Cephadex 500 mg

Side Effects of Cephadex 250 mg (Cephalexin)

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Rash
• Diarrhea
• Kidney issues

Interaction

• Nephrotoxic drugs, such as aminoglycosides: Increased kidney risk.
• Probenecid: increases Cephalexin levels.
• Antacids: may impair absorption.

Pharmacokinetics

• Absorption: Well absorbed orally.
• Distribution: Widely distributed in body tissues.
• Excretion: Primarily excreted unchanged in urine.

Clinical Trial

Cephalosporins are effective against a wide range of infections, including:

• Respiratory tract infections
• Urinary tract infections
• Skin and soft tissue infections
• Infections of bones and joints

Safety

• Generally well-tolerated; common adverse effects include diarrhea, abdominal pain, nausea, and vomiting.
• Rarely, it can give rise to severe allergic reactions, kidney problems, or liver damage.
• Not recommended in the event of allergies to penicillin or cephalosporins
• Contraindications-Use with caution in pregnant or lactating women, and those with kidney disorders.

Efficacy

• Highly effective against a broad spectrum of gram-positive, and some gram-negative bacteria
• Begins working in 1 hour after administration and lasts for 6-8 hours
• Commonly used to treat infections like cellulitis, cystitis, pneumonia, and osteomyelitis.
• It can be taken alone or in combination with other treatments.

Precautions

• Allergic reaction: Avoid if you are allergic to penicillinor other cephalosporins.
• Pregnancy and Breastfeeding: Consult your doctor prior using Cephalexin, it is generally considered safe during pregnancy and breastfeeding but should be used under medical supervision.
• Hepatic Disease: Dose adjustment is necessary. Inform your doctor prior if you have any kidney-related issues.
• Alcohol consumption: Although Cephalexin doesn’t interact directly with alcohol, but still it is advisable to avoid alcohol while on antibiotics to reduce the risk of side effects and ensure faster recovery.

Conclusion

Cephadex 250 mg is a reliable and widely used medication for the treatment of bacterial infection, that falls under Cephalexin category of an antibiotic under cephalosporin class. Its broad-spectrum antibacterial action makes it a first-line treatment for various infections, including those affecting the skin, urinary tract, and respiratory system.

FAQs

1) What for Cephadex 250mg used for?

Cephadex 250 mg is a reliable and widely used medication for the treatment of bacterial infection.

2) How does Cephadex 250 mg work?

Cephadex 250mg comes under cephalosporin class of antibiotic that contains cephalexin, which binds to penicillin-binding proteins in the bacterial cell wall and inhibits the formation of the cell wall.

3) What can be the side effects of Cephadex 250mg?

Nausea, Vomiting, Diarrhea, Abdominal pain, Rash, Diarrhea, Kidney issues can be the possible side effects.

4) How long does Cephadex 250mg works?

Cephadex 250 mg starts working within 1 hour of administration.

5) Is Cephadex 250mg safe for everyone?

Yes, Cephadex 250 mg is generally considered to be safe for everyone but it is recommended to use after consulting a medical professional.

References

https://www.ncbi.nlm.nih.gov/books/NBK549780/ 

https://pubmed.ncbi.nlm.nih.gov/31747187/